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. 2013 Aug 11;63(1):29–47. doi: 10.1111/prd.12027

Table 2.

Collagen-binding integrins and their ligand-recognition motifs

Integrin Collagen specificity Recognition sequence specificity References
α1β1

  • Collagen I >

  • Collagen IV

  • GFOGER (I, II, IV and more) >

  • GVOGEA (collagen II)

  • GLOGEN (collagen III)

  • GFPGEN (Scl2)

 (49, 68, 129, 132 152)
α2β1

  • Collagen I >

  • Collagen IV

  • GFOGER (I, II, IV and more) >

  • GLPGER (rScl1)

  • GFPGER (Scl2)

 (27, 129, 146 152)
α10β1

  • Collagen IV >

  • Collagen I

  • Collagen II

  • Collagen III

 GFOGER (I, II, IV and more) (26, 129)
α11β1

  • Collagen I >

  • Collagen IV

 GFOGER (I, II, IV and more) > GLPGER (rScl1) (27, 146, 165)
>

greater than.