Table 1.

Number of animals with presence of major cardiac anomalies (by EKG) in DNA-immunized dogs with chronic experimental Chagas disease.

Group	Dogs/n (%)	Suggested pathological conditions by EKG features found [29, 30]
TcSP gene (pBCSP plasmid)	2/7 (29%)	AV block
	1/7 (14%)	Left ventricular enlargement
TcSSP4 gene  (pBCSSP4 plasmid)	1/7 (14%)	MIMI
	1/7 (14%)	Second-degree AV block
pBK-CMV (empty plasmid)	6/7 (86%)	Most often abnormal when found on serial EKG and combined  with other disturbances
	4/7 (57%)	Left ventricle enlargement
	1/7 (14%)	Right BBB
SS (mock-immunized)	3/7 (43%)	Most often abnormal if it is found on serial EKG and combinedwith other disturbances
	1/7 (14%)	VPC
	2/7 (29%)	Pericardial effusion
	2/7 (29%)	Myocardial infarction and/or pericarditis and right ventricular enlargement

EKG: electrocardiogram.

AV: atrioventricular.

MIMI: microscopic intramural myocardial infarctions.

BBB: bundle branch block.

SS: physiologic saline solution.

VPC: ventricular premature complexes.