Table 2.

Other macroscopic alterations in DNA-immunized dogs with chronic experimental Chagas disease.

Macroscopic pathological features at 11 months after infection (at the time of euthanizing)	Groups	Dogs/n (%)
Whitish areas in heart of fibrous consistency Abundant pericardial fluid Whitish areas in spleen	SS (mock-immunized) and pBK-CMV (empty plasmid)	5/7 (71%) 6/7 (86%)
Ascites Megaesophagus Left ventricular hypertrophy Thinning of the right ventricular wall Severe tricuspid endocarditis	pBK-CMV (empty plasmid)	1/7 (14%)
Heart with adhesions in trachea and pericardium Splenic thickened walls Whitish areas in spleen and heart	TcSSP4 gene (pBCSSP4 plasmid)	1/7 (14%)