Table 3.

Inflammatory lesion (lymphocyte infiltrates) scores from three different sections of heart tissues of DNA-immunized dogs with chronic experimental Chagas disease.

Site	TcSP gene   (pBCSP plasmid)	TcSSP4 gene (pBCSSP4 plasmid)	pBK-CMV   (empty plasmid)	SS (mock-immunized)
Subepicardium	0.800 ± 0.2*	0.99 ± 0.4*	1.0714 ± 0.4*	1.0 ± 0.0*
Myocardium	0.7429 ± 0.1*	0.5143 ± 0.1	0.7143 ± 0.4*	0.9429 ± 0.4*
Subendocardium	0.1429 ± 0.03	0.2857 ± 0.04	0.7143 ± 0.4*	0.8932.3*

*Differences were considered as significant when P ≤ 0.05 (Kruskal-Wallis test among immunized/infected and healthy non-infected control animals, whose values obtained were 0.0, was performed).