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Effect of flumazenil on the latency (a), frequency (b), and duration of seizures (c) of AAE (400 mg kg−1, p.o.) and diazepam (0.3 mg kg−1, i.p.) (c) in PTZ-induced seizures. Data are presented as mean ± S.E.M. (n = 8). *P < 0.05,**P < 0.01, and ***P < 0.001 compared to vehicle-treated group (one-way analysis of variance followed by Newman-Keuls' post hoc Test). ††† P < 0.001 (two-way ANOVA followed by Bonferroni posttest).
