Skip to main content
. 2013 Oct;183(4):1209–1222. doi: 10.1016/j.ajpath.2013.06.017

Figure 5.

Figure 5

Gal3−/− DCs primed with high-dose LPS induced higher Th17 responses compared with gal3+/+ DCs. A: ELISA of cytokines in supernatants of CD4+ OT-II T cells that had been cultured with OVA-pulsed gal3+/+ or gal3−/− DCs for 3 days in the presence of low-dose (0.1 ng/mL) or high-dose (100 ng/mL) LPS. B: ELISA of IL-17 in OVA-LPS (100 ng/mL) DC–T-cell (OT-II) co-cultures after the addition of anti–IL-6, anti–IL-23p19, anti–IL-12/23p40, or isotype control antibodies on day 0. The co-cultures were maintained for 3 days. Data are given as means ± SD and are representative of at least three independent experiments. ∗∗P < 0.01, ∗∗∗P < 0.001.