Table 1.
Treatment | Untreated (topical)/ DMSO (systemic) | 7,8 DHF | Deoxygedunin | |||
635 pg | 64 pg | 1,166 pg | 167 pg | |||
Topical | ||||||
WT mice | ||||||
Axon profile length | + | NS | + | + | ||
Axon profile number | + | + | + | + | ||
trkB KO | ||||||
Axon profile length | − | − | − | |||
Axon profile number | − | − | − | |||
BDNF KO | ||||||
Axon profile length | − | + | + | |||
Axon profile number | NS | NS | NS | |||
Systemic | ||||||
WT mice | ||||||
Axon profile length | NS | + | + | |||
Axon profile number | NS | NS | ||||
M response | NS | + | + |
+, increased relative to untreated WT controls; −, decreased relative to untreated WT controls; NS, not significantly different from untreated WT controls.