Table 2.
Two-Point LOD Scores for Linkage of Microsatellite Markers on Chromosome 19p13.3-13.2 to AIS at Different θ[m=f] Values in All Seven Kindreds, under an Autosomal Dominant Model
LOD Scorea at θ[m=f]= |
|||||
Marker | 0 | .1 | .2 | .3 | .4 |
D19S209 | −.888 | .819 | .782 | .569 | .295 |
D19S894 | −1.179 | 1.822 | 1.561 | 1.052 | .482 |
D19S216 | 3.625 |
2.934 | 2.136 | 1.301 | .541 |
D19S1034 | −.026 | 1.217 | .918 | .507 | .148 |
D19S869 | −.671 | 1.398 | 1.024 | .557 | .161 |
D19S406 | −3.396 | 1.073 | .892 | .490 | .135 |
D19S901 | 2.523 | 3.512 |
2.589 | 1.548 | .613 |
D19S567 | .546 | 2.201 | 1.677 | 1.035 | .439 |
D19S873 | −.752 | .910 | .702 | .387 | .113 |
D19S912 | .491 | 1.825 | 1.349 | .784 | .294 |
D19S884 | 4.020 |
3.184 |
2.254 | 1.310 | .495 |
D19S922 | 4.087 |
3.150 |
2.179 | 1.239 | .450 |
D19S916 | −2.287 | 2.137 | 1.672 | .992 | .378 |
D19S413 | −1.607 | .822 | .692 | .409 | .127 |
D19S865 | 1.180 | .876 | .555 | .270 | .071 |
D19S914 | −1.990 | .015 | .169 | .135 | .046 |
D19S221 | −3.606 | 1.169 | 1.074 | .715 | .307 |
Significant LOD scores are underlined.