Table 4.
Kruskal-Wallis test with Dunn-Sidak adjusted pairwise comparisons, values presented as mean (standard deviation). Pulmonary artery hypertension (PAH) systolic pulmonary artery pressures (sPAP) are statistically significant.
| Variable | A1ATD (n = 2) |
CF (n = 4) |
COPD (n = 22) |
IPF (n = 43) |
Other (n = 4) |
PAH (n = 8) |
Sarcoid (n = 8) |
Scleroderma (n = 12) |
UIP (n = 8) |
KW P-value |
|---|---|---|---|---|---|---|---|---|---|---|
| sPAP (mmHg) | 32.0 (4.24) | 38.0 (6.16) | 37.6 (12.17) | 40.6 (14.78) | 39.0 (9.20) | 73.5 (17.54) | 61.4 (20.75) | 50.8 (19.13) | 61.6 (26.54) | <0.001 |
| dPAP (mmHg) | 16.0 (1.41) | 18.0 (8.12) | 21.7 (7.22) | 18.3 (8.98) | 21.5 (6.35) | 31.3 (7.81) | 29.8 (9.87) | 20.8 (7.88) | 29.5 (13.48) | 0.003 |
| mPAP (mmHg) | 22.0 (1.41) | 24.5 (7.05) | 28.1 (7.44) | 25.2 (10.52) | 27.5 (6.14) | 47.1 (10.26) | 40.9 (13.62) | 32.3 (11.77) | 41.9 (19.63) | <0.001 |
| mPCWP (mmHg) | 4.5 (6.36) | 13.0 (5.29) | 14.1 (7.50) | 9.7 (12.08) | 11.0 (3.56) | 13.9 (6.58) | 14.4 (4.69) | 12.8 (8.90) | 15.9 (6.36) | 0.05 |
| CI (L/min/m2) | 3.1 (0.85) | 4.1 (0.25) | 3.0 (0.47) | 3.5 (3.96) | 2.7 (0.23) | 2.2 (1.18) | 3.0 (0.66) | 2.6 (0.71) | 2.5 (0.44) | 0.144 |
| EF (%) | 0.54 (0.01) | 0.62 (0.03) | 0.56 (0.06) | 0.58 (0.06) | 0.58 (0.06) | 0.58 (0.03) | 0.60 (0.09) | 0.60 (0.02) | 0.55 (0.06) | 0.068 |
| A/E | 1.07 (0.38) | 0.94 (0.43) | 1.06 (0.29) | 1.09 (0.35) | 0.79 (0.57) | 0.85 (0.51) | 1.03 (0.17) | 1.04 (0.52) | 1.18 (0.33) | 0.729 |
| A′/E′ | 1.40 (0.3) | 0.47 (0.35) | 0.85 (0.72) | 1.06 (0.72) | 0.72 (0.51) | 0.88 (0.49) | 0.34 (0.48) | 0.99 (0.62) | 0.77 (0.59) | 0.165 |
| DD (n/total) | (0/2) 0.0% | (0/4) 0.0% | (5/22) 22.7% | (10/43) 23.3% | (1/4) 25.0% | (1/8) 12.5% | (1/8) 12.5% | (5/12) 41.7% | (2/8) 25.0% | 0.850 |
sPAP: systolic pulmonary artery pressure.
dPAP: diastolic pulmonary artery pressure.
mPAP: mean pulmonary artery pressure.
mPCWP: mean pulmonary capillary wedge pressure.
CI: cardiac index.
EF: left ventricular ejection fraction.
DD: diastolic dysfunction.