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. 2013 Sep 17;170(3):661–670. doi: 10.1111/bph.12315

Figure 6.

Figure 6

Effects of SOD or catalase on the ACh- and GSK- induced cerebrovascular dilation of the PCA in APP mice. Compared with WT vessels, ACh- (A) and GSK- (B and C) induced cerebrovascular dilations were reduced in APP vessels. Treatment with SOD or catalase completely normalized these responses to levels comparable to those of WT arteries. SOD (A and B) or catalase (C) had no effect on vessels from WT mice. *P < 0.05, **P < 0.01, ***P < 0.001, when compared with untreated WT vessels; ⋆ P < 0.05, ⋆⋆ P < 0.01, ⋆⋆⋆ P < 0.001, compared with SOD- or catalase-treated APP vessels, by anova followed by a Newman–Keuls comparison test. Error bars represent SEM. n = 3 per group.