Skip to main content
. 2013 Sep 17;170(3):679–692. doi: 10.1111/bph.12321

Figure 1.

Figure 1

Effects of CBDV BDS components in the PTZ model of acute convulsion. (A, B) Experiment 1.1: dose response of modified BDS. (C, D) Experiment 1.2: purified CBDV compared with modified BDS. (E, F) Experiment 1.3: comparison of modified CBDV BDS against matching levels of CBDV and CBD. (G, H) Experiment 1.4: BDS-pCB. (A, C, E, G) Maximum observed convulsion severity (median severity in grey, box represents interquartile range, whiskers represent maxima and minima (Kruskal–Wallis test, with a post hoc Mann–Whitney U-tests). (B, D, F, H) Mortality (chi-squared test, with post hoc Fisher exact test); n = 15 for each dose; #P ≤ 0.1, *P ≤ 0.05, **P ≤ 0.01. In all panels ‘V’ represents vehicle treatment.