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. 2013 Sep 17;170(3):679–692. doi: 10.1111/bph.12321

Table 1.

Experimental design and pCB content of in vivo Experiments 1.1–4.2

Experiment/Figures Compound Doses (mg·kg−1) CBDV/CBD content (mg·kg−1) THC/THCV content (mg·kg−1)
Experiment 1.1, Figure 1A and 1B Modified CBDV BDS 50 29/7 0/0
100 58/14 0/0
200 116/27 0/0
275 159/38 0/0
346 200/47 0/0
Experiment 1.2, Figure 1C and 1D Purified CBDV 50 50/0 0/0
100 100/0 0/0
200 200/0 0/0
Modified CBDV BDS 50 29/7 0/0
100 58/14 0/0
200 116/27 0/0
Experiment 1.3, Figure 1E and 1F Purified CBDV + CBD Low 50/12 0/0
Mid 100/23 0/0
High 200/47 0/0
Modified CBDV BDS 50 50/12 0/0
100 100/23 0/0
200 200/47 0/0
Experiment 1.4, Figure 1G and 1H pCB-free BDS 50 2/<1 0/0
100 4/<1 0/0
200 9/<1 0/0
Experiments 2.1 and 2.2, Figure 2A–F Unmodified CBDV BDS 150 71/21 2/4
275 130/38 3/7
422 200/59 4/11
Modified CBDV BDS 150 87/21 0/0
275 159/38 0/0
346 200/47 0/0
Experiment 3.1, Figure 3A Unmodified CBDV BDS 50 24/7 1/1
100 47/14 1/3
200 95/28 2/5
Experiment 3.2, Figure 3B Modified CBDV BDS 50 29/7 0/0
100 58/14 0/0
200 116/27 0/0
Experiment 4.1, Figure 4A Unmodified CBDV BDS 100 47/14 1/3
200 95/28 2/5
300 142/42 3/8
Experiment 4.2, Figure 4B Modified CBDV BDS 200 116/27 0/0
Unmodified CBDV BDS 200 116/28 2/5
CBDV + CBD 116/27 0/0