Table 1. Characteristics of patients with ulcerative colitis and Crohn's disease on admission and healthy volunteers.
Variables | UC (n = 75) | CD (n = 31) | HLT (n = 75) |
Age, yr, median (IQR) | 38 (30–54) | 34 (25–39) | 37 (30–50) |
Male/female | 42/33 | 19/12 | 42/33 |
Disease duration, yr, median (IQR) | 3 (1–9) | 9 (3–16) | - |
Disease location, n | |||
Total colitis/left-sided colitis | 56/19 | - | - |
Small bowel/colon/both | - | 10/7/14 | - |
CAI score, median (IQR) | 10 (5–13) | - | - |
CDAI score, median (IQR) | - | 138 (101–172) | - |
Mayo endoscopic score, n, 0/1/2/3 | 0/15/20/40 | - | - |
Laboratory data, median (IQR) | |||
WBC [×103/mm3] | 8.5 (6.1–11.3) | 5.6 (4.3–7.9) | - |
PLT [×104/mm3] | 33 (26–45) | 38 (26–44) | - |
ESR [mm/hr] | 36 (14–67) | 31 (19–55) | - |
ALB [g/dL] | 3.2 (2.6–3.8) | 3.5 (3.1–4.0) | - |
CRP [mg/dL] | 0.8 (0.2–4.8) | 0.5 (0.1–2.4) | - |
Treatment before admission, n (%) | |||
Aminosalicylate | 67 (89) | 24 (77) | - |
Corticosteroids | 52 (69) | 2 (6) | - |
Mercaptopurine/azathioprine | 13 (17) | 6 (19) | - |
Cyclosporine | 3 (4) | 0 (0) | - |
Leukocytapheresis | 20 (27) | 0 (0) | - |
Elemental diet | 0 (0) | 19 (61) | - |
Abbreviations: ALB, albumin; CAI, clinical activity index; CD, Crohn's disease; CDAI, Crohn's disease activity index; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; HLT, healthy volunteers; IQR, interquartile range; PLT, platelet; UC, ulcerative colitis; WBC, white blood cell count.