Fig. 3.

Analysis of patient 1 suggesting EEG-fMRI concordance during spike propagation. (a) Signal and maximum field power of the average spike, local peaks (t₁, t₂) considered for MEM-concordance are represented using red vertical lines. (b) MEM source localization, thresholded as in Fig. 2b, estimated at t₁ and t₀, an additional time point showing some early activity located at PO4 electrode (green vertical line in panel a) and in the right superior posterior temporal area on the cortex. (c) t-values of the two most significant fMRI clusters obtained with the HRF peaking 5 s after the spike, superimposed on the 3D anatomical MRI. (d) Same fMRI clusters after interpolation onto the cortical surface. (e) MEM-concordance and fMRI-relevance metrics for cluster 1 and cluster 2. (f) 3D representation of the position of the intracranial EEG electrodes with one MRI sagittal slice and the cortical surface (yellow slightly transparent), active contacts being represented in red. Comparisons between fMRI and MEM results at t₁ suggested partial spatial overlap between sources. α=3.65 for cluster 1 suggested a good EEG-fMRI concordance, which could be slightly detectable in MEM results at t₀. These results were confirmed by intracranial EEG recordings (f).