Fig. 5.

Analysis of patient 9 showing partial EEG-fMRI concordance within a focal cortical dysplasia. (a) Signal and maximum field power of the average spike, local peaks (t₁, t₂) considered for MEM-concordance are represented using red vertical lines. (b) MEM source localization estimated at t₁, thresholded as in Fig. 2b. (c) t-values of the two most significant fMRI clusters obtained with the HRF peaking 3 s after the spike, superimposed on the 3D anatomical MRI. (d) Same fMRI clusters after interpolation onto the cortical surface. (e) MEM-concordance and fMRI-relevance metrics for cluster 1, cluster 2 and when considering both clusters together. (f) Left parietal focal cortical dysplasia manually segmented and superimposed in red on an axial MRI slice, together with the cortical surface (yellow slightly transparent). Visual inspection (b and d) and quantitative results (e) confirmed an excellent EEG-fMRI concordance within the dysplastic lesion (f). α suggested that considering only cluster 1 as prior information in the EEG inverse problem was more relevant than considering both cluster 1 and cluster 2.