Table 1.
Pts | Age (year) | Epilepsy type | Seizure semiology | Age of first seizure (year) | Scalp EEG recordings outside the scanner | Antiepileptic drugs | Seizure frequency |
---|---|---|---|---|---|---|---|
1 | 25 | R TLE | Rising epigastric aura followed by out-of-breath sensation and loss of consciousness | 24 | Interictal: RTor RFT spike or polyspike-slow waves Ictal: none |
None | Two events in 1 year |
2 | 39 | R TOLE | Stroboscopic black and white light in the L visual field, or forced eye-deviation to the L with loss of consciousness | 12 | Interictal: spikes and spike-slow waves over the R posterior quadrant Ictal: rhythmic burst of spikes over the R T region sometimes spreading over the L side |
Carbamazepine 2400 mg, Valproic acid 1000 mg, Clobazam 10 mg | 1/month |
3 | 52 | TOLE | Before surgery visual distortion of objects and lights with language difficulty and now also associated with auditive distorsion | 17 | Interictal: independent R and L temporal spikes Ictal: none |
Pregabalin 450 mg, Topiramate 300 mg | 1/day (at least) |
4 | 23 | L TLE | Feeling of familiarity, ‘déjá vu’ or ‘deja vecu’ sensation then loss of contact with staring, lip smacking and swallowing movements (lower limbs movements sometimes) | 14 | Interictal: L T and R T independent irregular sharp waves or spikes Ictal: not recorded in scalp EEG |
Carbamazepine 600 mg, Topiramate 300, Clobazam 20 mg | 3–4/day in clusters |
5 | 11 | R FLE | Sensation of fear followed by a deep breath movement. He could sometimes scream and turns his head to the left | 4 | Interictal: R F spike-waves isolated or organized in short burst Ictal: Prolonged bursts of rhythmic bilateral F spike-waves with a clear R predominance |
Phenytoin 100 mg, Valproic acid 250 mg | 20–30/day |
6 | 33 | L CPLE | Somesthesic sensation in the R elbow followed by a slow non-tonic R arm elevation | ? | Interictal: polyspikes or poly-sharp waves over the L CP area. Ictal: rhythmic fast activity starting over the L CP regions followed by a spreading over the FT areas |
Carbamazepine 1200 mg, Topiramate 75 mg, Clobazam 20 mg | 1–3/day |
7 | 26 | Bil TOLE | Chest pressure feeling followed by loss of contact, staring, chewing and sometimes R eyes-deviation | 9 | Interictal: spike and slow waves complexes over TO electrodes bilateral or predominant over the R side Ictal: bilateral slow waves followed by rhythmic fast activity seen synchronously over the posterior temporal regions with a predominance over the R side. Irregular generalized slow waves followed |
Carbamazepine 1000 mg, Clobazam 40 mg | 1/week |
8 | 23 | Bil TOLE | Start to see things smaller and far away from her, then she becomes blind or sees lights forming faces | 13 | Interictal: synchronous and rhythmic slow wave discharges with intermixed sharp components over both posterior head regions Ictal: prolonged electrographic attack, maximal over both posterior temporal regions with clear predominance over the R side |
Clobazam 40 mg, Lamotrigine 500 mg, Phenytoin 300 mg | 1–2/week |
Mean ± SD | 29 ±12.3 | 13,3 ± 6.3 |
R = right; L = left; Bil = bilateral; T = temporal; O = occipital; C = central; P = parietal.