Table 3.
BOLD responses (activation and deactivation) during interictal epileptiform events
| Lesion | Pt | Activation
|
Deactivation
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Areas involved in BOLD response
|
Areas of the max BOLD response
|
Areas involved in BOLD response
|
Areas of the max BOLD response
|
||||||||||||
| Lesion | Overl Cx | Dist | Max t-value | Lesion | Overl Cx | Dist | Lesion | Overl Cx | Dist | Max t-value | Lesion | Overl Cx | Dist | ||
| Nodular gray matter heterotopia | 1 | Y | – | – | 5.6 | Y | – | – | – | – | Y | −4 | – | – | Y |
| 2 | Y | Y | – | 6.3 | Y | – | – | – | Y | – | −7 | – | Y | – | |
| 3 | – | – | Y | 5.2 | – | – | Y | – | – | Y | −4.5 | – | – | Y | |
| – | – | Y | 4.8 | – | – | Y | – | – | Y | −5 | – | – | Y | ||
| 4 | – | Y | – | 4.3 | – | Y | – | – | – | Y | −4.2 | – | – | Y | |
| Y | Y | Y | 8.2 | – | – | Y | – | Y | Y | −5.2 | – | – | Y | ||
| Focal cortical dysplasia | 5 | Y | Y | – | 10.8 | Y | – | – | – | – | Y | −4.7 | – | – | Y |
| 6 | Y | – | Y | 5.8 | Y | – | – | – | – | – | – | – | – | – | |
| Band gray matter heterotopia | 7 | Y | Y | – | 5.4 | Y | – | – | – | Y | – | −8.8 | – | Y | – |
| Y | Y | – | 5.3 | Y | – | – | – | Y | – | −9.2 | – | Y | – | ||
| 8 | – | – | Y | 7.4 | – | – | Y | Y | Y | – | −6.3 | Y | – | – | |
| Mean ± SD | 6.3 ±1.2 | −5.9 ±1.6 | |||||||||||||
The lesion in focal cortical dysplasia and in band heterotopia is always involved by BOLD changes during interictal events generation. Results for patients with nodular heterotopia were more variable. Overl Cx = overlying cortex; Dist. = distant area; Y = significant BOLD changes observed in this area.