Table 1.
EBMT
|
Düsseldorf-Registry
|
||||||
---|---|---|---|---|---|---|---|
(n = 247)
|
(n = 137)
|
||||||
at diagnosis
|
at diagnosis
|
||||||
RAEB | 173 (70%) | 100 (73%) | |||||
RAEB-t | 74 (30%) | 37 (27%) | |||||
at transplant | |||||||
RAEB | 135 (54%) | ||||||
RAEB-t | 83 (34%) | ||||||
transformed to sAML | 29 (12%) | ||||||
Intensive chemotherapy before transplantation | |||||||
yes | n=135 | ||||||
no | n = 89 | ||||||
unknown | n = 23 | ||||||
Status at transplantation | |||||||
CR | n = 75 | ||||||
non CR | n=149 | ||||||
missing | n = 23 | ||||||
Patients sex | |||||||
male | 169 (68%) | 83 (61%) | |||||
female | 78 (32%) | 54 (39%) | |||||
Conditioning | |||||||
standard | 77 (31%) | ||||||
reduced | 170 (69%) | ||||||
Median age at diagnosis | 58 years | 62 years | |||||
55-60 | 167 (67%) | 51 (37%) | |||||
60-69 | 80 (33%) | 86 (63%) | |||||
Cytogenetics known | n = 88 | n = 79 | |||||
normal | 35 (40%) | 40 (51%) | |||||
abnormal | 53 (60%) | 39 (49%) | |||||
Percentiles of time from diagnosis to transplant in days | 1st | 35 | 99th | 10586 | |||
5th | 73 | 95th | 1395 | ||||
10th | 97 | 90th | 1191 | ||||
25th | 141 | 75th | 475 | ||||
median | 226 | ||||||
Time period diagnosis | 1971-2004 | 1998-2005 | |||||
Time period transplant | 1998-2004 (50% in 2003 + 2004) | ||||||
Donor | |||||||
HLA identical | n = 176 (71%) | ||||||
matched unrelated | n = 71 (29%) |