Table 3. Between group differences in mismatch responses by region and emotion stimulus.
Deviant vs. Standard | Between Group Difference in Mismatch Signal | ||||||
Control Group | Schizophrenia Group | ||||||
Condition | Time Window | Region of Interest (ROI) | LSMean(SE) | p value | LSMean(SE) | p value | Effect size (Cohen’s D) |
170–220 ms | Pre-Frontal | 0.10 (0.25) | – | 0.41 (0.25) | – | 0.26 | |
Central | 0.48 (0.20) | 0.024 | 0.10 (0.20) | – | 0.38 | ||
Temporal Left | −0.21 (0.15) | – | −0.28 (0.15) | 0.064 | 0.09 | ||
Temporal Right | −0.54 (0.21) | 0.014 | −0.08 (0.21) | – | 0.45 | ||
Occipital Left | −0.52 (0.24) | 0.035 | −0.54 (0.24) | 0.027 | 0.02 | ||
Fear | Occipital Right | −0.55 (0.23) | 0.018 | −0.39 (0.23) | 0.087 | 0.15 | |
250–360 ms | Pre-Frontal | 0.25 (0.26) | – | 0.28 (0.26) | – | 0.02 | |
Central | 0.57 (0.25) | 0.024 | −0.06 (0.25) | – | 0.53 | ||
Temporal Left | −0.38 (0.20) | 0.056 | 0.01 (0.20) | – | 0.42 | ||
Temporal Right | −0.67 (0.18) | <.001 * | −0.02 (0.18) | – | 0.75 a | ||
Occipital Left | −0.61 (0.18) | 0.001 * | −0.41 (0.18) | 0.027 | 0.23 | ||
Occipital Right | −0.60 (0.18) | 0.002 * | −0.43 (0.18) | 0.021 | 0.19 | ||
170–220 ms | Pre-Frontal | −0.31 (0.23) | – | 0.09 (0.23) | – | 0.36 | |
Central | 0.61 (0.14) | <.001 * | 0.07 (0.14) | – | 0.81 a | ||
Temporal Left | −0.57 (0.20) | 0.007 * | 0.32 (0.20) | – | 0.89 a | ||
Temporal Right | −0.24 (0.20) | – | −0.12 (0.20) | – | 0.12 | ||
Occipital Left | −0.51 (0.27) | 0.064 | −0.12 (0.27) | – | 0.30 | ||
Happy | Occipital Right | −0.38 (0.27) | – | −0.20 (0.27) | – | 0.14 | |
250–360 ms | Pre-Frontal | −0.06 (0.21) | – | 0.19 (0.21) | – | 0.25 | |
Central | 0.45 (0.13) | 0.002 * | 0.00 (0.13) | – | 0.68 a | ||
Temporal Left | −0.38 (0.19) | 0.053 | 0.30 (0.19) | – | 0.73 | ||
Temporal Right | −0.26 (0.19) | – | 0.01 (0.19) | – | 0.29 | ||
Occipital Left | −0.70 (0.21) | 0.001 * | −0.18 (0.21) | – | 0.53 | ||
Occipital Right | −0.43 (0.22) | 0.054 | −0.10 (0.22) | – | 0.31 |
p<0.05 significant difference in ERPs to deviant and standard stimuli (significant mismatch signal) after Hochberg correction for multiple comparisons.
p<0.05 significant difference in mismatch signal between groups.