Figure 1. Virulence profile in a murine model of cutaneous sporotrichosis.
BALB/c mice were subcutaneously infected with 107 conidia of clinical isolates of S. schenckii or S. brasiliensis. (A) Evolution of primary lesions in the dorsal sacral region of mice infected with S. brasiliensis and S. schenckii isolates. (B) Fungal load of the primary cutaneous lesions determined 40 days post-infection. a p<0.05 relative to 1099-18 isolate; b p<0.05 relative to IPEC 15383 isolate; c p<0.05 relative to IPEC 17943 isolate; dp<0.05 relative to Ss54 isolate; e p<0.05 relative to HUPE 114158 isolate.