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. 2012 Mar;20(2):214–219. doi: 10.4062/biomolther.2012.20.2.214

Table 1.

Inhibitory potential of protocatechuic acid (1), geniposide (2), 6'-O-trans-p-coumaroylgeniposide (3), 3,5-dihydroxy-1,7-bis(4-hydroxyphenyl) heptanes (4) and ursolic acid (5)

Compound Yield (%) IC50 valueb Specific activityd

MAO-A μM MAO-B μM DBH μM MAO-A MAO-B Unitc/g DBH

1 0.01 2,411 300 334 2,695 21,739 19,608
2 0.16 >12,887 223 >12,887 <200 11,628 <200
3 0.0003 >9,363 127 >9,363 <200 14,706 <200
4 0.0009 400 196 941 7,937 16,129 3,367
5 0.007 >10,965 780 214 <200 2,809 10,204
Iproniazida - 40 60 -
Deprenyla - 3.3 0.05 -

aPositive control for MAO. bInhibitory potency is obtained by Logic-log graph paper. cOne unit is defined as a sample amount to give 50% inhibition against the enzymes. dSpecific activity means the amount of unit in 1 g of a test sample.