Table 2.
Haplotype Frequencies Estimated Using Different Estimation Protocols for SAA Data
|
Frequency (Mean ± SD)b for |
|||
| Haplotypea | One-Subject Pool | Two-Subject Pool | Four-Subject Pool |
| ACTGCC | .394 | .406 (.40134 ± .01218) | .391 (.40547 ± .01843) |
| ACCGTC | .214 | .210 (.21079 ± .01356) | .226 (.21262 ± .02260) |
| AGCGCT | .210 | .209 (.21364 ± .01071) | .214 (.21885 ± .01868) |
| GCCGTC | .036 | .025 (.03303 ± .00937) | .022 (.02669 ± .01665) |
| GCTGCT | .035 | .040 (.03045 ± .00749) | .027 (.02583 ± .01282) |
| GGCACT | .023 | .015 (.01994 ± .00591) | .008 (.01730 ± .00968) |
| ACTGCT | .023 | .010 (.01633 ± .00710) | .023 (.01221 ± .00944) |
| AGCACT | .018 | .021 (.01849 ± .00628) | .021 (.01507 ± .00948) |
| GGCGCT | .017 | .020 (.01487 ± .00861) | .023 (.01371 ± .01525) |
| ACTGTC | .013 | .009 (.00883 ± .00395) | … (.00433 ± .00452) |
| ACCGCC | .006 | .007 (.00501 ± .00221) | .007 (.00293 ± .00277) |
| ACCATC | .006 | … (.00361 ± .00399) | … (.00275 ± .00498) |
| AGCGCC | .003 | .004 (.00274 ± .00186) | … (.00158 ± .00230) |
| GCCATC | … | .012 (.00144 ± .00319) | .014 (.00295 ± .00563) |
| ACCGTT | … | .009 (.00335 ± .00532) | … (.00412 ± .00660) |
| AGCGTT | … | .004 (.00106 ± .00267) | … (.00109 ± .00264) |
| GCTGCC | … | … (.00325 ± .00633) | .009 (.00671 ± .01207) |
| GCTACT | … | … (.00086 ± .00199) | .004 (.00176 ± .00355) |
| GCTGTT | … | … (.00044 ± .00114) | .003 (.00100 ± .00220) |
| GCCGTT | … | … (.00369 ± .00608) | … (.00744 ± .01086) |
| GCCATT | … | … (.00063 ± .00164) | … (.00109 ± .00271) |
| ACTACC | … | … (.00041 ± .00183) | … (.00103 ± .00338) |
a
Haplotypes with mean frequency >.001 in at least one of the estimation protocols are included.
b
Frequency is based on a single estimation. Mean and SD are based on different random samplings used to make the pools (for two- and four-subject pool protocols).