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. 2003 Jan 17;72(2):384–398. doi: 10.1086/346116

Table 5.

Haplotype Frequencies Estimated Using Different Estimation Protocols for the MTHFR Gene

Frequency (Mean ± SD)a for
Haplotype One-Subject Pool Two-Subject Pool Four-Subject Pool
CA .450 .463 (.47038 ± .02383) .450 (.48188 ± .03560)
TA .394 .381 (.37343 ± .02388) .394 (.36193 ± .03566)
CC .156 .143 (.13579 ± .02373) .156 (.12429 ± .03556)
TC .013 (.02038 ± .02383) … (.03187 ± .03561)
a

Frequency is based on a single estimation. Mean and SD are based on different random samplings used to make the pools (for two- and four-subject pool protocols).