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. 2013 Oct 8;4:194. doi: 10.3389/fgene.2013.00194

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Copyright © Gonzales-Roybal and Lim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The adult mouse SVZ: a tractable system for molecular-genetic studies of NSC differentiation. (A) Coronal view of SVZ. (B) Enlarged view of SVZ: type B cells (blue) can contact the ventricle with a thin process extended between ependymal cells (brown); type C cells (green) are transit-amplifying cells that give rise to migratory type A cells (red). (C) Sagittal view showing paths of migratory neuroblasts (red, type A cells) to the OB. (D) The neuronal lineage of self-renewing type B cells. (E) SVZ NSC culture in self-renewal (left) and differentiation (right) conditions. The astrocyte marker GFAP in green, the neuronal marker Tuj1 in red, and DAPI in blue.