Table 1. Various combinations of Kdm4A and Kdm4B mutations and associated adult phenotypes.
Abbreviation | Genotype | Adult Phenotype |
---|---|---|
Kdm4A+/− | Kdm4AKG04636/CyO | Viable, fertile, grossly normal morphology |
Kdm4B+/− | Kdm4BEY10737/CyO | Viable, fertile, grossly normal morphology |
Kdm4A+/−, Kdm4B+/− | Kdm4AKG04636, Kdm4BEY10737/CyO | Viable, fertile, grossly normal morphology |
Kdm4A−/−, Kdm4B+/− | Kdm4AKG04636, Kdm4BEY10737/Kdm4AKG04636,+ | Viable, fertile, grossly normal morphology |
Kdm4A+/−, Kdm4B−/− | Kdm4AKG04636, Kdm4BEY10737/+, Kdm4BEY10737 | Viable, fertile, grossly normal morphology |
Kdm4A−/−, Kdm4B−/− | Kdm4AKG04636, Kdm4BEY10737/Kdm4AKG04636, Kdm4BEY10737 | No viable adults recovered |
Kdm4AKG04636/CyO, Kdm4BEY10737/CyO, and the recombinant Kdm4AKG04636, Kdm4BEY10737/CyO flies were used in crosses. Genotypes were deduced from the presence or absence of the CyO balancer chromosome in adult flies.