Table 1. Incidence of phenotypic features in E12.5 yautja embryos.
Phenotypic feature of mutant | Overall incidence of phenotypea | Incidence as sole mutant feature | Incidence of phenotype in WT or HET embryos |
---|---|---|---|
Cranial neural tube defect | 32/57 | 6/57 | 1/174 |
Caudal neural tube defect | 43/57 | 3/57 | 0/174 |
Compressed forebrain | 21/57 | 5/57 | 0/174 |
Craniofacial abnormalityb | 12/57 | 0/57 | 0/174 |
Most mutants showed various combinations of the four phenotypic features listed
Craniofacial abnormality includes cleft lip and cleft face