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. 2013 Oct 9;33(41):16334–16345. doi: 10.1523/JNEUROSCI.0708-13.2013

Figure 5.

Figure 5.

ELI altered the expression of iron storage related genes. Neonatal mice (P3) were injected subcutaneously with saline (CON) or E. coli (ELI), and blood, liver, and brain from male and female mice were collected at P4 and P12. A, Total iron was determined from serum at P4 and P12. B, Liver mRNA levels of hepcidin were determined (n = 6). Brain mRNA levels of (C) hepcidin, (D) ferroportin, (E) transferrin receptor and (F) L-ferritin were determined at P4 and P12 (n = 6). Bars represent the mean ± SEM (n = 6). Means with asterisk are significantly different from controls (p < 0.05), and means with plus sign tended to be different from controls (p ≤ 0.1).