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. 2013 Sep 15;27(18):1986–1998. doi: 10.1101/gad.226753.113

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© 2013, Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 5. — DNA-hypomethylating agent reverses the differentiation defect in mutant IDH2 cells. (A) After 8 d of adipocyte differentiation induction, microscopic images of cell morphology were recorded in IDH2 R172K mutant cells with or without transient 5-aza treatment. (B) After 8 d of adipocyte differentiation induction, mRNA expression of Adipoq and Fabp4 in IDH2 R172K mutant cells with or without transient 5-aza treatment was measured by qRT-PCR. The average ± SD from three biological replicates are shown.