Table 1.

Key parameters at inclusion, 4, 8, 12, and 16 weeks.

Time	Systolic pressure			Diastolic pressure			Laser Doppler flux			Heart rate			Plasma-free radicals
	Enovita 300 mg	Enovita 150 mg	Control	Enovita 300 mg	Enovita 150 mg	Control	Enovita 300 mg	Enovita 150 mg	Control	Enovita 300 mg	Enovita 150 mg	Control	Enovita 300 mg	Enovita 150 mg	Control
Inclusion	149; 4.5	150; 3	153.3; 4.4	91; 3.2	91.3; 2	90.4; 2.5	1.1; 0.01	1.1; 0.2	1.1; 0.01	78; 3.5	77.3; 4	77.2; 3.3	378; 22	382; 21	383; 23
4 weeks	121.3; 5.4∗#	129; 2.2∗#	142.3; 5*	86.3; 3.9*	88; 2*	88.4; 3*	1.28; 0.01∗#	1.2; 0.1	1.16; 0.01	73; 2.2*	73; 3.2*	74; 3.2*	—	—	—
8 weeks	119; 4.9∗#	125; 3∗#	142; 3.9	84.4; 2.8∗#	86.1; 2.1*	87; 3.6	2.13; 0.1∗#	1.6; 0.2∗#	1.22; 0.1	71; 3.1*	73; 2.1	74; 3.1	324; 19∗#	339; 32∗#	376; 29*
12 weeks	113; 3.3∗#	122; 3.2∗#	139; 3.5	83; 3.3#	86.3; 2#	88; 2.2	2.22; 0.2∗#	1.9; 0.2∗#	1.3; 0.1	69; 2.3*	72.2; 2#	74; 2.3	—	—	—
16 weeks	112; 3.5∗#	123; 2.1∗#	141; 4.3	82.3; 3#	85.3; 2#	88.9; 3.2	2.23; 0.1#	1.9; 0.2#	1.2; 0.1	70; 1.5	72; 2.3	73.2; 2.2	317; 22∗#	342; 28#	374; 22

*(P < 0.05) indicates statistical variations in comparison with previous value.

#: better than controls.