Figure 5.

Effects of paeonol on renal histology in mice. Sections of  kidney were stained with H&E 72 h after cisplatin injection. Saline treatment alone (a); cisplatin treatment alone (b); paeonol and cisplatin treatment (c). Renal tubular injury was assessed using a semiquantitative score in which the percentage of cortical tubules showing epithelial necrosis was assigned a score of either 0, none; 1, <10%; 2, 10–25%; 3, 25–75%; or 4, >75% (d). Saline: saline alone; Cis: cisplatin alone; Cis + paeonol: paeonol pretreatment and cisplatin treatment (*P < 0.05 versus Cis, n = 3).