Table 1.
Immunohistochemical (IHC) expression of p53 protein using automated cellular imaging system ACIS-III quantitative analysis, according to histopathological diagnosis.
| Histopathology | Total number of patients |
IHQ quantitative analysis in the whole group |
Number of patients positive for p53 |
IHQ quantitative analysis for positive cases |
|||
|---|---|---|---|---|---|---|---|
| Mean value | Median value | Mean value | Median value | ||||
| Benign lesions | Normal thyroid tissue | 16 | 1.76 | 1.11 | 0 | — | — |
| Nodular goiter | 50 | 4.82 | 1.71 | 8 | 17.25 | 15.52 | |
| Follicular adenoma | 55 | 8.75 | 3.68 | 19 | 20.47 | 15.72 | |
| Papillary thyroid carcinoma | 164 | 51.85 | 53.59 | 127 | 52.32 | 63.69 | |
|
| |||||||
| Malignant lesions | Classic | 106 | 42.16 | 32.24 | 83 | 62.17 | 70.70 |
| Follicular variant | 54 | 38.15 | 39.18 | 41 | 54.30 | 57.92 | |
| Tall cell variant | 04 | 03 | 49.31 | 55.08 | |||
| Follicular carcinoma | 42 | 11.11 | 2.17 | 11 | 36.36 | 21.64 | |