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. 2004 Apr;15(4):1568–1579. doi: 10.1091/mbc.E03-06-0444

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Copyright © 2004, The American Society for Cell Biology

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Figure 5. — Coimmunostaining of TopBP1 and Cor1 proteins in a Fkbp6^-/- mouse pachytene nucleus. Fluorescence microscopy of mouse meiotic chromosomes from a pachytene nucleus stained with mouse anti-Cor1 (red, left) and rabbit anti-TopBP1 (green, middle). Right panel: merged image. TopBP1 is mainly located to chromosome cores that are not completely synapsed. The arrowheads indicate chromosome cores (c) and synaptonemal complexes (SC). The X and Y chromosomes and the pseudoautosomal region (PAR) are also showed.