CDF decreased tumor growth (A), the relative protein levels of EZH2, CD44, EpCAM, Notch-1, and Nanog by Western blot analysis (B), the cell proliferation, Ki-67, and CD44 (C) immunohistochemistry using pancreatic tumor tissues orthotopically derived from human pancreatic cancer MiaPaCa-2 cells showing reduced expression of Ki-67 and CD44. H&E, hematoxylin and eosin.