Table IV.
Odds ratio for wheezing based on positive test results for rhinovirus and titers of IgE antibodies (in international units per milliliter) to dust mite (D pteronyssinus)
Titer of IgE antibodies to mite: |
<0.35 IU/mL |
0.35-17.4 IU/mL |
≥17.5 IU/mL |
||||
---|---|---|---|---|---|---|---|
No. | PCR negative | PCR positive (A/C)∗ | PCR negative | PCR positive (A/C)∗ | PCR negative | PCR positive (A/C)∗ | |
Wheezing children | 95 | 5 | 4† (2/2) | 8 | 16 (3/10) | 20 | 42 (8/30) |
Nonwheezing children‡ | 186 | 73 | 15 (6/5) | 43 | 7 (2/3) | 45 | 3 (1/2) |
Stable asthma | 63 | 13 | 2 (0/1) | 12 | 5 (1/2) | 31 | 1 (0/1) |
Control | 123 | 60 | 13 (6/4) | 31 | 2 (1/1) | 14 | 2 (1/1) |
Odds ratio§ | 3.89 (0.9-16), P = .07 | 12.3 (3.8-39), P < .001 | 31.5 (8.3-108), P < .001 |
The number in parentheses indicates the number of subjects with positive test results for group A and group C strains of rhinovirus.
Two of these 4 children had IgE antibody to B tropicalis: 24.3 and 1.66 IU/mL.
Children with stable asthma combined with nonasthmatic control subjects.
Odds ratio for wheezing among rhinovirus-positive (real-time PCR) compared with rhinovirus-negative subjects.