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A proposed model of aATC immunotherapy induced in vivo immunization of patient’s endogenous immune system: aATC-mediated killing of tumor cells releases cytokines and tumor antigens; cytokines secreted as a function of aATC induce maturation and activation of monocytes to become DC and Ag-primed DCs present antigen to naïve T-cells. Primed T-cell and B-cell interactions leads to B-cell proliferation and differentiation into tumor-specific antibody-producing cells
