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. Author manuscript; available in PMC: 2013 Oct 8.
Published in final edited form as: Nat Med. 2012 Jun;18(6):918–925. doi: 10.1038/nm.2757

Figure 1.

Figure 1

Aldh1a1 is present primarily in visceral fat, and its expression correlates with obesity. (a) Aldh1a1 mRNA and protein expression in different fat depots of female C57BL/6J mice (n = 10). (b) ALDH1A1 mRNA and protein expression in visceral adipose tissue (viscAT) and subcutaneous adipose tissue (scAT) from nonobese male and female subjects (n = 20). (c) Aldh1a1 mRNA and protein expression in GWAT from standard chow–fed (SC) lean and high-fat diet–fed (HF) obese C57BL/6J mice (n = 8 per group). (d) ALDH1A1 mRNA and protein expression in viscAT from nonobese (body-mass index (BMI) = 25.2 ± 0.15 kg m−2) and morbidly obese (BMI = 53.0 ± 0.55 kg m−2) subjects; n = 20 per group. Representative western blots are shown. (e) Linear regression analysis between BMI and ALDH1A1 mRNA expression in human viscAT (n = 40). **P < 0.01, ***P < 0.001. Data are given as mean ± s.e.m.