Skip to main content
. Author manuscript; available in PMC: 2013 Oct 8.
Published in final edited form as: Nat Med. 2012 Jun;18(6):918–925. doi: 10.1038/nm.2757

Figure 3.

Figure 3

Aldh1a1 deficiency activates a thermogenic program in white fat. (a, b) Citrate synthase activity (a) and oxygen consumption rate (b) in GWAT and BAT of WT versus Aldh1a1−/− mice as measured by enzymatic assays and the Seahorse Extracellular Flux Analyzer, respectively. (c) Core body temperature of WT versus Aldh1a1−/− mice. Results represent average body temperature over a 48-h period at 23 °C and 4 °C, respectively. (d, e) Representative Ucp1 western blot (d) and H&E and immunohistochemical Ucp1 staining (e) in GWAT, SWAT and BAT of WT versus Aldh1a1−/− (KO) mice after 48 h of cold stimulation. n = 6–8 per group, *P < 0.05. Scale bar, 100 μm. Data are given as mean ± s.e.m.