Fig. 1.
20S proteasome inhibition by fluorine substituted curcumin analogs. Purified rabbit proteasome (35 ng) was incubated with or without (E) various concentrations of curcumin (Cur) and its fluorine substituted curcumin analogs for 2 h, followed by proteasomal chymotrypsin-like activity assay. Columns, mean values±SD. *p<0.03; **p<0.01; ***p<0.001.