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Figure 7. Multiple transcription factors, including YY1, directly bind near the conserved RBEIII element.

Figure 7

The RBEIII sequence (red) and flanking sequences are shown, indicating the positions bound by USF1/2, TFII-I and YY1. Sequence variations observed in HIV-1 subtypes LAI-B (pTY-LAI-dsRed), LAI-A, LAI-C and LAI-E are indicated. A binding site for AP1 identified in subtypes A and C is indicated [34].