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. 2013 Oct 8;8(10):e77112. doi: 10.1371/journal.pone.0077112

Table 1. The various stages of platelet activation. Adapted from Ko and Cooper 1993, ref [36].

Type Stage Morphology
I Round Round or spherical without evidence of pseudopodia
II Dendritic Round with early-stage pseudopodia without flattening
III Spread-Dendritic Pseudopodia at intermediate stage, with evidence of pseudopodia flattening. No evidence of hyaloplasm spreading between pseudopodia
IV Spreading Evidence of pseudopodia formation, with spreading of hyaloplasm
V Fully-Spread Fully-spread hyaloplasm with no distinct pseudopodia. Central bodies adopt a flattened state