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Localization of CD74-ILs in target cells. CD74-ILs, after 1-hour incubation with Raji cells (A, B, G, J) visualized by confocal microscopy. CD74-ILs are observed inside the cells and also on the cell membrane. Controls such as IgG-ILs (C and L) and nontargeted liposomes (D, E, K) did not enter/bind the cells. CD74-ILs in CD74− cell line Jurkat (I) did not bind/enter the cells. All lipids are R18-labeled.
