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Macrophages are essential for pathological HA and lymphangiogenesis. (A and C) PBS-treated controls. (B and D) Mice that received subconjunctival clodronate liposomes. Magnification, ×100 (C and D). (E) Depletion of macrophages inhibits both HA and lymphangiogenesis (LA) in inflammatory neovascularization (P < 0.01). Magnification (A and B), ×20.
