Skip to main content
. Author manuscript; available in PMC: 2013 Oct 9.
Published in final edited form as: Kidney Int. 2008 Aug 13;74(10):1310–1318. doi: 10.1038/ki.2008.395

Figure 4. NGAL inhibits cyst growth in vitro.

Figure 4

(a, b) Pkd1 null cells were grown in a 70:30 collagen:Matrigel mixture for 5 days in the (a) absence or (b) presence of added NGAL (20 μg/ml). (c, d) Quantification of cyst area and volume from cells grown as in (a, b). Images were obtained from 10 random fields of three separate experiments. (c) Relative cyst area (calculated as mean pixels2 by outlining 76 cysts (36 from PN18 cells and 40 from PN24 cells) for each condition) and (d) cyst volume (calculated as pixels3 assuming a spherical shape) were determined using the Adobe Photoshop software. *P<0.001.