Table 4.
Results from the Multivariate Analysis of Factors Associated with Overall Survival (OS), Relapse-Free Survival (RFS), Treatment-Related Mortality (TRM), and Graft-versus-Host Disease (GVHD) after Unrelated Donor HSCT
| Transplant-Related Mortality |
|||
|---|---|---|---|
| RH | 95%CI | P-Value | |
| aGVHD II-IV | 12.3 | 3.63-41.7 | <.001 |
| LC30* | 0.88 | 0.77-1.00 | <.05 |
| G-CSF | 3.42 | 1.21-9.68 | .02 |
| Relapse-free survival | |||
| aGVHD II-IV | 0.39 | 0.18-0.82 | .014 |
| LC30* | 3.42 | 1.07-10.9 | .036 |
| CD34 dose* | 0.95 | 0.91-0.99 | .024 |
| Overall survival | |||
| aGVHD II-IV | 0.19 | 0.09-0.40 | <.001 |
| Platelets D +30* | 1.10 | 1.04-1.17 | .006 |
| CD34 dose* | 0.94 | 0.90-0.98 | .002 |
LC30 indicates day 30 absolute lymphocyte count; platelets, day 30 platelet count; CD34 dose, CD34+ cell dose in graft (× 106/kg); aGVHD; acute graft-versus-host disease; G-CSF; granulocyte-colony stimulating factor administration postgraft; HSCT, hematopoietic stem cell transplantation.
Analyzed as continuous variables.