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. 2013 Oct 4;7:1089–1102. doi: 10.2147/DDDT.S48971

Figure 5.

Figure 5

Assessment of cell proliferation via MTT assay.

Notes: (A) Cell proliferation and survival of SMMC-7721 cells (initial density 5 × 104 cells/well) in the presence of 4 μg/mL (0.39 pmol/μL) of the IGF-IIP3 DRzs for a maximum of 72 hours. (B) comparison of cell proliferation and survival of SMMC-7721, HepG2, and Huh7 cells (initial density 5 × 104 cells/well) in response to 4 μg/mL (0.39 pmol/μL) of the IGF-IIP3 DRzs after 24 hours. All data are means ± SD from triplicates (n ≥3). *P < 0.05; **P < 0.01; ***P < 0.001.

Abbreviations: DRz, deoxyribozyme (DNAzyme); IGF-IIP3, insulin-like growth factor II promoter 3; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; SD, standard deviation.