TABLE 5.

Erythrocyte MCV by quartiles of serum cholesterol measures in adult participants in NHANES 2005–2008

	NHANES Survey 2005–2006 (N = 4,469)		NHANES Survey 2007–2008 (N = 5,318)
	Cell Volume Mean (fL)	95% CI	Cell Volume Mean (fL)	95% CI
HDL-C (mg/dl)
Unadjusteda
Low	89.14	88.72, 89.56	87.97	87.33, 88.61
Medium	89.55	88.96, 90.14	88.33	87.73, 88.93
High	90.15	89.61, 90.68	88.95	88.18, 89.71
Very high	91.74	91.27, 92.20	89.47	88.56, 90.39
Trend P value	<0.001		<0.001
Adjustedb
Low	88.96	88.50, 89.41	87.90	87.30, 88.50
Medium	89.58	89.03, 90.13	88.34	87.75, 88.93
High	90.41	89.88, 90.94	89.01	88.23, 89.78
Very high	91.69	91.29, 92.09	89.49	88.65, 90.34
Trend P value	<0.001		<0.001
Non-HDL-C (mg/dl)
Unadjusteda
Low	90.32	89.60, 91.04	88.91	88.02, 89.81
Medium	90.32	89.72, 90.93	88.49	87.60, 89.37
High	89.91	89.41, 90.40	88.45	87.89, 89.02
Very high	90.19	89.66, 90.73	88.65	88.03, 89.28
Trend P value	0.526		0.376
Adjustedb
Low	90.36	89.75, 90.97	88.95	88.11, 89.79
Medium	90.37	89.85, 90.89	88.54	87.73, 89.36
High	89.92	89.33, 90.51	88.51	87.91, 89.11
Very high	90.17	89.62, 90.72	88.54	87.96, 89.11
Trend P value	0.360		0.101

Cholesterol quartiles were determined from NHANES 2005-2006 and are as follows: HDL-C [low (≤41.83 mg/dl), medium (>41.83–51.38 mg/dl), high (>51.38–62.93 mg/dl), and very high (>62.93 mg/dl)]; and nonHDL-C [low (≤114.42 mg/dl), medium (>114.42–140.1 mg/dl), high (>140.1–168.28 mg/dl), and very high (>168.28 mg/dl)]. CI, confidence interval.

^aUnadjusted model.

^bAdjusted for age, race/ethnicity, gender, smoking, and BMI.