Table 2.

Results of the Histological Analysis of the Repair Tissue 3 Weeks After Creation of Osteochondral Defects in the Lapine Trochlear Groove According to Sellers et al.¹⁰

Parameter	Assignable points	Unilateral design	Bilateral design
Filling	[0–4]	0.476±0.590 [0–3]	0.927±0.821* [0–3]
Integration	[0–3]	1.933±0.800 [0–3]	1.229±0.421* [1–2]
Matrix staining	[0–4]	0.410±0.958 [0–3]	2.802±0.929* [1–4]
Cellular morphology	[0–5]	2.295±0.980 [0–5]	4.017±0.975* [2–5]
Architecture defect	[0–4]	0.800±0.924 [0–4]	1.601±1.074* [0–4]
Architecture surface	[0–3]	1.333±1.157 [0–3]	1.535±0.598 [0–3]
Subchondral bone	[0–4]	1.124±1.026 [0–3]	3.101±0.636* [1–4]
Tidemark	[0–4]	3.800±0.526 [1–4]	3.903±0.297 [3–4]
Total score	[0–31]	12.171±3.215 [6–21]	19.115±2.672* [8–24]

Unilateral design: one joint operated per animal; bilateral design: both joints operated within the same animal. Values are given as mean±standard deviation as well as range of point values (square brackets). ^*p<0.001 for unilateral versus bilateral design.