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. 2013 Oct 9;8(10):e75644. doi: 10.1371/journal.pone.0075644

Table 4. Statistical relationships between the use of pharmaceutical and dietary prophylaxis and the incidence of acute mountain sickness (AMS) in Nepalese pilgrims upon arrival to Gosainkunda (4380 m).

Prophylactic agent Use Sample size (n (%)) X2 Relative Risk
Total AMS+ Statistic p-value Statistic 95% CI
Acetazolamide No 457 155 (33.9)
Yes 34 12 (35.3) 0.027 0.87 1.04 0.65, 1.67
Paracetamol No 459 154 (33.6)
Yes 32 13 (40.6) 0.67 0.41 1.21 0.78, 1.88
NSAID No 478 162 (33.9)
Yes 13 5 (38.5) 0.12 0.73 1.14 0.56, 2.28
Garlic No 178 42 (23.6)
Yes 313 125 (39.9) 13.50* <0.001 1.69* 1.26, 2.28
Ginger No 371 120 (32.3)
Yes 120 47 (39.2) 1.88 0.17 1.21 0.93, 1.58
Lemon No 366 117 (31.5)
Yes 125 50 (40.0) 2.68 0.10 1.25 0.96, 1.63
Mountain pepper No 448 147 (32.8)
Yes 43 20 (47.6) 3.28 0.07 1.42* 1.00, 2.1
*

This result is statistically significant (i.e., p<0.05).