Table 4. Statistical relationships between the use of pharmaceutical and dietary prophylaxis and the incidence of acute mountain sickness (AMS) in Nepalese pilgrims upon arrival to Gosainkunda (4380 m).
Prophylactic agent | Use | Sample size (n (%)) | X2 | Relative Risk | |||
Total | AMS+ | Statistic | p-value | Statistic | 95% CI | ||
Acetazolamide | No | 457 | 155 (33.9) | ||||
Yes | 34 | 12 (35.3) | 0.027 | 0.87 | 1.04 | 0.65, 1.67 | |
Paracetamol | No | 459 | 154 (33.6) | ||||
Yes | 32 | 13 (40.6) | 0.67 | 0.41 | 1.21 | 0.78, 1.88 | |
NSAID | No | 478 | 162 (33.9) | ||||
Yes | 13 | 5 (38.5) | 0.12 | 0.73 | 1.14 | 0.56, 2.28 | |
Garlic | No | 178 | 42 (23.6) | ||||
Yes | 313 | 125 (39.9) | 13.50* | <0.001 | 1.69* | 1.26, 2.28 | |
Ginger | No | 371 | 120 (32.3) | ||||
Yes | 120 | 47 (39.2) | 1.88 | 0.17 | 1.21 | 0.93, 1.58 | |
Lemon | No | 366 | 117 (31.5) | ||||
Yes | 125 | 50 (40.0) | 2.68 | 0.10 | 1.25 | 0.96, 1.63 | |
Mountain pepper | No | 448 | 147 (32.8) | ||||
Yes | 43 | 20 (47.6) | 3.28 | 0.07 | 1.42* | 1.00, 2.1 |
This result is statistically significant (i.e., p<0.05).