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. 2013 Oct 8;21(10):1743–1756. doi: 10.1016/j.str.2013.08.004

Figure 2.

Figure 2

Final Structure Ensemble of FUN-EGF3

(A) Twenty-structure ensemble of FUN-EGF3, with structures aligned to the FUN-EGF1 region (cartoon representation). Disulphides are shown as sticks. The FUN and EGF1 domains are colored lilac and green, respectively, and the EGF2–EGF3 region is colored white.

(B) Lowest-energy structure from the FUN-EGF3 ensemble, with the EGF1-EGF2 linker sequence (G112–H118) in red.

(C and D) Backbone of the (C) FUN-EGF1 region, showing residues 52–112, and (D) EGF2–EGF3 region, showing residues 118–178. Energy-minimized average structures are shown below the aligned ensembles.